Diabetes mellitus manifests itself in a wide variety of complications and the symptoms of the disease are multifactorial. The lipid hydroperoxide level and lipid profile were investigated in plasma of normal and Alloxan-induced diabetic rats treated with olive oil for six weeks. Diabetic rats exhibited an increase in the levels of hydroperoxide, cholesterol, triglycerides and low density lipoprotein (LDL), and a decrease in the level of high density lipoprotein (HDL). The administration of olive oil showed a better profile in the lipid as well as decreases in the concentration of lipid hydroperoxides either in normal or diabetic rats. The results are discussed according to antioxidant property of olive oil.

Key Words: Olive oil, Diabetes, Lipid profile, Antioxidant.